Wearable sensors and mobilehealth services. Giuseppe Andreoni R&D Manager
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1 Wearable sensors and mobilehealth services Giuseppe Andreoni R&D Manager
2 Politecnico.di.Milano Politecnico di Milano promotes the integration of skills and collaboration with medical and social disciplines to develop innovative technologies, methodologies and services for a human-centered healthcare. Human Design Technology 2
3 Politecnico.di.Milano TeDH - Technology and Design for Healthcare Lecco campus 3
4 User Centred Design Concepts Design for HealthCare Politecnico.di.Milano Measurements and Assessment of human functions for Design Anthropometric and Functional data for extended users design HMI and Proactive Ergonomics Communication aids Ambient Intelligence & domotics New paradigms of HCI (e.g. non intrusive monitoring) / gestural interfaces Ethnography Physiological data Sensibilab Biomechanical and Anthropometrical factors Lab. of Biomedical Sensors and Systems LyPhE Lab. of Physical Ergonomics Behavioral observation data Cognitive data HCD HealthCare Design Skillpoint User testing PhyCo Lab Physical Computing Lab. 4
5 From research to market TT and spin-off Why? To implement the virtuous innovation chain through a difficult path - for different attitudes (researcher enterpreneur) - burocracy - funds to start up - autocensoring (but somebody else would have already thought ) - to create new opportunities - Research ROI - new young enterpreneursip - sinergies industry-research - brain keeping 5
6 Innovation? Find the difference: Venice, the plague Africa, Ebola Virus
7 From research to market: ComfTech Where we met Presidio Ospedaliero Alessandro Manzoni di Lecco Dip.Materno-Infantile U.O. di Neonatologia e Terapia Intensiva Neonatale 7
8 From research to market: ComfTech Why and How we met and merge University (Basic research on wearable systems) Competitive Sinergies Spin-Off Textile Company (Product innovation for preterrm newborns) 8
9 From research to market: ComfTech 9 Innovation strategy Research IPR I2P BP BP competition Spin Off Applications development Products portfolio Testing Production process optimization -> low costs CE Med Certification
10 From research to market: ComfTech ComfTech s.r.l. Comfortable Technology is a Politecnico di Milano Start-up. It was born in October 2010 at Monza, for the integration of sinergic competences: - Biomedical Technologies, in particular for the unobtrusive measurement of physiological parameters - Textiles, with Designer specialized for baby garments, from newborns to teenagers - Ergonomics and Design for usability, wearability, comfort and userfriendlyness of the system. Comfortable Technology realizes sensorized textiles for biosignal monitoring and optimized shape and fit.
11 From research to market Wearables and beyond 11
12 Scenario Future Healthcare goals Continuity of care inside and outside the hospital; shared care involving all care givers from prevention to rehabilitation, across all stages of care (prevention, diagnosis, treatment, follow-up) Citizen-centred care citizen empowerment to manage own health status; increase responsibility and knowledge provision of personalised care/individual treatment emphasis on preventative lifestyle (from care to prevention) - early diagnosis / prognosis - management of chronic diseases - independent living / ambient assisted living (aging society) 12
13 Scenario Healthcare 2020 from Cure to Care.. a new complex and multifactorial process in which technological factors, organizational, and human dimensions must find a balanced mix for a full success. 13
14 Scenario New concepts: Personalized medicine Empirical Medicine Stratified Medicine Personalized Medicine Drugs administered to all patients without differentiation Drugs administered to sub-populations of patients Complexity Drugs administered to a single patient One-size-fits-all Era Current Approach of Medicine Towards Medicine of the future 14
15 Scenario Personalized medicine Based on the individual molecular profile for customized diagnosis and new therapies for the best efficacy and the least collateral damages to the single patient, thus minimizing costs From B/W to multicolour medicine The right process and the right drug, to the right patient, for the right pathology, at the proper time, with the best dose, for the right therapeutic answer, at the right cost. 15
16 Scenario Clinical Reference Concept The Care is the new clinical approach for the theraphy of newborns in NICU (Neonatal Intensive Care Unit) and/or in the first two-hours lifetime, to assure the baby physical and comfortable experiences that could guarantee the best conditions for the most proper neuromotor development. Technicality Care 16
17 Scenario The Wearable Biomedical Systems Wearable Health Systems (WHS) or Wearable Biomedical Systems (WBS) are integrated systems on body-worn platforms like wrist-worn devices or biomedical clothes, offering pervasive solutions for continuous health status monitoring though non-invasive biomedical, biochemical and physical measurements. WBS would enable monitoring of patients over extensive periods of time, and they can be proposed to offer affordable and interactive healthcare, anyplace, anytime for anyone which is the future of healthcare.
18 Scenario The Wearable Biomedical Systems 18
19 Scenario The wearable market and its forecast HC 19
20 Scenario The wearable market and its forecast 20
21 WBS & research WBS integrate a multifactorial and multi-technological complexity: every element is essential even in its extreme simplicity: Sensors Actuators Materials Wireless communication Power supply CPU User interface Algorithms for data processing Connectors Sensors washability and stability Sensors position in body (in relation to activities, tasks, signals adn anthropometry) Elasticity and adherence. multidisciplinarity 21
22 WBS History Research: history 22
23 WBS history ORIGINS OF THE CONCEPT OF SMART GARMENT FOR BIOMEDICAL SENSING - M.I.T. ( ) - DARPA (Defense Advance Research Projects Agency) & Georgia Institute of Technology Sensatex - SmartShirt 23
24 WBS definition WBS are intelligent and integrated systems in contact or close to the human body and capable to measure, process and transmit biomedical, biochemical and physical parameters, and even to perform mechanical actions if needed. Human as source of information (A), sensors (B) and their link (C) to measuring devices (D) and wireless data transmission (E). 24
25 WBS: signals and preferable sensors positioning FHT2. Future of Health Technology-2, 2005, IOS Press, Health. Care. Anywhere. Today., D. Andre and A. Teller
26 WBS: sensors and materials
27 WBS: sensors and implementation
28 WBS: sensors and implementation Wearable strain gauges by Piezoresistive Ink Elbow flexion
29 WBS: sensors and implementation Pressure Sensors
30 WBS: sensors and implementation WBS are a wide area for IPR: More than 1000 patents in the last 10 years
31 From theory to pratice: Examples in medicine 31
32 Wearable Sensors in NICU From The Problem Ensure monitoring (Cure) but... improve comfort, protection, physical and psychological wellbeing of the newborn (Care) - Replace the standard adhesive electrodes; - Maintain clinical quality signal; - Interface to monitor hospital. - Increase thermal protection - Introduce the function of "containment" - Respect the clinical procedures (e.g., access quickly to the chest for emergencies). To The Solution Design and production of sensorized systems/garments* for monitoring the preterm newborn or the infants in the first two hours of life with dedicated and fitting shape to the needs of babies (Cure+Care) Patented & licensed Start up Home monitoring 12 june :35:54 25 C rest
33 Wearable Sensors in NICU Innovative Pros User No effects on the skin No influence on vital phenomena and daily actions Quality of care and compliance Textiles: Selected and certified fibers for biomedical applications Washing and Sterilization resistance TT and spin-off Technology Compatibility with Hospital devices no gel required
34 NewBorn Monitoring Clinical trial setup Sala parto Control Room Sensing garment BT-WiFi 3 users: nurse, mother, father CLINICAL TRIAL: newborns - 2 hours continuous monitoring Measurement Rationale: Reliability assessment Usability assessment Ergonomic assessment 34
35 NewBorn Monitoring 2.5 2h - NewBorn monitoring x
36 NewBorn Monitoring Data example (zoom+) 2h - NewBorn monitoring Breathing x 10 4
37 NewBorn Monitoring Smart garment Wearable device for data measurement and transmission Smartphone App for data processing and display (HR, BR, posture and activity level). 37
38 Mother & Foetus monitoring 38 TeleFetal Care Hospital and Home Mother-fetal Monitoring QRS Fetal Amplitude > µvpp Frequency ~120 bpm QRS Mat Amplitude > 1mVpp Frequency ~70bpm
39 Mother & Foetus monitoring Design for wearability Best design 39
40 Mother & Foetus monitoring 1) Detection of maternal QRS 2) Subtraction of maternal QRS 3) Detection of fetal QRS Maternal HRV Estraction of fetal ECG Fetal HRV 40
41 Elderly monitoring in ADL 41
42 Sleep Monitoring Integrated textile sensors and snaps for device General Specifications - The t-shirt measures heart rate, the estimate of breathing rate, and movements while sleeping. - device and textile electrodes embedded. - On board recording and data download through Bluetooth Preliminary test Subject: 1 male, 44 yrs 5,5 hrs sleep 1 ECG lead 3D Accelerations Sensorized t-shirt 42
43 Accelerations along the 3 single axes = body movements Sleep Monitoring 1200 Sleep Monitoring - GA - 28march Falling asleep Start sleeping in posture 1 Change of posture Change of posture Change of posture Change of posture Change of posture Change of posture Awakening Time in samples (Fc=128Hz) 43 x 10 6
44 Sleep Monitoring & Sensor validation ECG track (total signal) Zoom area x
45 Sensor validation Zoom on ECG track (clinical quality) x 10 5
46 Sensor validation Zoom+ on ECG track (clinical quality) x 10 5
47 Sensor validation Ideal ECG track and recording example (clinical quality) 47
48 Sensor validation Textile ECG track compared with ideal ECG track 48
49 Systems portfolio Sporty Eldy Ally Mammy Baby 49
50 Lifestyle and performance monitoring Walk Run Walk ECG Vertical accel 3000 Antero-post accel lareral Accel Breathing ADC levels 1500 Sky Race Running Samples (Fc=125Hz) Soccer x 10 4 Automotive Wearable monitoring Cycling Fitness 50
51 Award and future perspectives March 2013 Comfortable Technology is selected and participates to the action line Health & Wellbeing - of EIT ICT Labs one of the first Knowledge and Innovation Communities set up by the European Institute of Innovation and Technology, as an initiative of the European Union to drive European leadership in ICT innovation for economic growth and quality of life. Health & Wellbeing Boosting the quality of everyday life by accelerating ICT innovation\
52 Contacts ComfTech s.r.l. Via Castello 9, Monza (MB) - Italy Tel info@comftech.com Giuseppe Andreoni giuseppe.andreoni@comftech.com Design Dept. Politecnico di Milano Tel Fax giuseppe.andreoni@polimi.it
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