Downhole Monitoring Solutions. Medical Instrumentation

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1 Downhole Monitoring Solutions 1 Medical Instrumentation

2 Forward Looking Statements This corporate presentation contains forward-looking statements, which reflect the Company s current expectations regarding future events. The forward-looking statements involve risks and uncertainties. Actual events could differ materially from those projected herein and depend on a number of factors, including the successful and timely completion and the commercialization of the products herein. The reader of this document is forewarned concerning the inherent variability and risk associated in terms of strategies or deliverables stated herein by the Company and is cautioned prior to considering these forward-looking statements. The Company disclaims any obligation to update these forward-looking statements. 2

3 Listing Symbol Shares / diluted Working Cap (Feb 17, 2014) TSX:V OPS 59 M/69 M 13 M Revenue 2013 $7.5 M US & Canadian Institutions Significant Ownership by Management & Directors 23% 3

4 Business Overview Opsens develops, manufactures and installs systems to measure a number of parameters, including pressure and temperature, using fiber optic sensing technologies. Medical Instrumentation Fractional Flow Reserve (FFR) Initially developed product for Japanese medical supplier, leveraging the Company s fiber optic technology Products in Development FFR Optical Guidewire First regulatory filing January 2014 (completed) Downhole Monitoring Oil and Gas Industry Operating business unit in Alberta providing critical pressure and temp. measurements in thermal operations (ex. SAGD) since 2008 Flagship Product - Commercialized OPP-W fibre optic pressure/temp sensor In Development OPP-G high pressure sensor Projected FFR Market Size: US$1B+ Industry Annual Capex in 2014: ~C$25B* Platform Technology with a Focus on Large Growing Markets 4 * Source: Canadian Association of Petroleum Producers: Estimated Industry Annual Capex Spending for 2014

5 Investment Highlights Platform technology focused on markets with attractive growth opportunities FFR Oil and Gas Unique and differentiated product capabilities Strong intellectual property with defined strategy to bring core products to market Strong and committed management with proven track record 5

6 Diagnosis with FFR* = Guided PCI** Therapy Aortic Pressure Blockage Distal Pressure Normal FFR Ratio Stent FFR = Distal Pressure Aortic Pressure * Fractional Flow Reserve ** Percutaneous Coronary Intervention 6

7 Attractive Industry Dynamics (FFR) Increasing Cost of Coronary Artery Disease US$315B spent on coronary artery disease in the US (AMA 2010 estimate) Increasing Pressure to Control Health Care Costs US health care spending expected to grow by 5.8 to ~20% of GDP by 2022 (CMS 2013 estimate) FFR measurements facilitate reimbursement by hospitals and third-party payers Focus on Reducing Invasive Procedures Patients and healthcare providers focused on reducing invasive procedures to lower costs and improve standard of care Attractive Market Dynamics Support FFR Industry Growth 7

8 Attractive Industry Dynamics (cont'd) Year Milestones Outcome 2009 FAME I Study EU: ESC Class I with Level of Evidence A US: ACC/AHA Class IIA with Level of Evidence A 2012 FAME II Study 2012 (cont d) FFR Industry Milestones Japan: New reimbursement code for FFR Angiography + FFR + Stent superior to Angiography + Stent Highest class and level possible; procedure is beneficial, useful and effective Benefits of FFR outweigh the risks and it can be useful as a tool Angiography + FFR + Stent + OMT superior to Angiography + OMT Code established reimbursement for FFR during diagnostic angiography for the 1 st time Key Takeaways In recent years, landmark studies have demonstrated clear clinical benefits to using FFR Facilitates invasive procedure decisionmaking Improves patient outcomes Helps avoid unnecessary medical procedures Multiple cardiology medical societies address the use of FFR in appropriate use criteria for diagnostic evaluation ESC has given FFR a Class I, Level A recommendation, the highest possible FFR market could grow significantly if ACC/AHA increases recommendation from Class IIA to Class I 8

9 Attractive Industry Dynamics (cont'd) Mgmt s Estimated Global Market Size (US$ M) $1,000 + Key Drivers Mgmt estimate 2013 FFR market: >US$250M Current FFR penetration: ~14-15% Industry players indicate potential: 45% Significant growth available from $167 $207 $250 Meeting unmet needs for cardiologists Increased penetration FFR expansion into new indications and markets (peripherals) $124 $75 $ Beyond Management expects FFR market growth to ~15-17% annually until 2017 Other players in FFR market have referenced market size to >US$1B 9 * Source: Research estimates and various company filings

10 Unique and Differentiated Product Capabilities (FFR) OptoMonitor and OptoWire Supported by 10 patents (8 granted, 2 pending) Strong IP (Sensor, detection scheme, guidewire, connectivity of sensor tools, medical application of technology) 10

11 Unique and Differentiated Product Capabilities (cont d) Conventional Pressure Guidewire Opsens Optical Pressure Guidewire Sensor Wires Torque Transfer Optical Fiber Opsens Patented Designs Provide Unique Capabilities 11

12 OptoWire Aiming to Fulfill Critical Unmet Needs Conventional Pressure Guidewire Opsens Optical Pressure Guidewire Mechanical performance Lesions difficult to reach Delays in procedures FFR assessment reliability Pressure drift leads to unreliable FFR assessment Connectivity compatibility with PCI Procedure Contrast agents prevent multiple connection, hindering post-stent and multi-vessels FFR assessment First nitinol-based optical pressure guidewire Construction similar to non-pressure workhorse guidewires known for kink-crush resistance, superior pushability and torquability Pressure system delivers high-fidelity, reliability FFR assessment Connectivity shows NO sensitivity to contrast agents, allowing post-stent and multi-vessels FFR assessment 12 * Source: Research estimates and various company filings

13 Defined Strategy to Bring Core Products to Market Commercialization Commercial launch of OptoWire expected in 2015 with key milestone events expected to be achieved in 2014 Japan: signed agreement with a medical distributor in Nov. 2012, providing the Japanese Company with distribution rights in Japan, Korea and Taiwan; Approval and commercial launch anticipated by end of 2014 US & EU: approval and commercial launch in early Q13 1Q14 2Q14 3Q14 4Q U.S. E.U. Design Verification & Validation File 510(k) File for CE Marking 510(k) Review CE Review Commercial Launch Commercial Launch Japan File PMDA PMDA Review Commercial Launch * Based on calendar year 13

14 Focused on Markets with Attractive Growth Opportunities (O&G) Oil and Gas Market SAGD Production Forecast (1) Producers are shifting to unconventional oil resources to meet demand SAGD technology is primary technology used in oil sands In Canada, SAGD-based production has grown at ~12% annually since 2006 SAGD-based production is expected to grow at ~7% over the next two decades Opsens successfully completed adoption phase O&G sensors have been in market for over 5 years Sensor used by 4 of the top 10 SAGD producers O&G sensors provide a recurring revenue stream with high-margins In some applications, sensors are replaced every months SAGD Production Forecast (bbl/day x 1,000) According to CAPP, SAGD production is expected to grow at a rate of ~7% over next two decades 14 (1) SAGD Instrumentation Market Assessment, Ian Murray & Company Ltd., Consultant report, June 26, 2012.

15 Unique and Differentiated Product Capabilities Producing Well Steam Injection Well SRU Installation Hot Steam Chamber ( ºC +) Heated Oil 15 Opsens OPP-W Sensor at pump for in-situ P/T monitoring (300ºC) Cold Oil Sand OPP-W at toe of well

16 Unique and Differentiated Product Capabilities (cont d) Subcool Zone Distribution - SOR Distribution impacts recovery rate along well pairs Low or Zero Subcool zone Optimal Subcool zone High Subcool zone OPP-W in Injector and Producer Pipes Opsens fibre optic sensors offer improved temp and pressure measurements at temp up to 300 C Improve subcool for higher recovery rate Improve subcool for better steam management 16

17 Growth Strategy Gaining market share in expanding FFR markets Expanding and investing in FFR-focused distribution channels and sales force Developing new applications for the Company s FFR technology Increasing long-term revenues in the Oil and Gas market Investing in innovation to enhance existing applications of the Company s technology 17

18 Strong & Committed Management, Proven Track Record Opsens senior management team fully committed with significant ownership stake (~30%) in the Company Opsens benefits from a scientific advisory board of cardiologists Senior Management Louis Laflamme, President & CEO Involved with various high-tech public and private companies Thierry Dumas, CFO Previously Corp. Controller for Atrium Innovations and various positions at PricewaterhouseCoopers and Ernst & Young Claude Belleville, VP Life Sciences Successfully sold his first fibre optic venture Gaétan Duplan, VP Oil & Gas Successfully sold his first fibre optic venture Scientific Advisory Board Dr. Morton J. Kern University of California, Irvine Cardiology, Chairman Dr. Olivier F. Bertrand - Quebec Heart-Lung Institute, QC, Cardiologist Dr. Michael J. Lim - St. Louis University, Cardiologist 18

19 Investment Highlights Platform technology focused on markets with attractive growth opportunities FFR Oil and Gas Unique and differentiated product capabilities Strong intellectual property with defined strategy to bring core products to market Strong and committed management with proven track record 19

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